The present invention relates to a slow-release pesticide system in agragrian applications that includes but is not limited solely to insecticide, fungicide and herbicide formulations. The system includes a pesticide incorporated into vesicles that is formed by neutral lipids (thereby enhancing the water solubility of the pesticide). The vesicles that incorporate the pesticide are, in turn, adsorbed, on a clay mineral. The formulations are appropriate for pesticide molecules of any type (hydrophobic, acid and basic). Said pesticide formulation allows slow release of the active ingredient, thereby reducing the risk of pollution of groundwater and surface water.