Walter C. Babcock,Dwayne T. Friesen,David Keith Lyon,Warren Kenyon Miller,Daniel Tod Smithey
申请号:
US13533637
公开号:
US20120264833A1
申请日:
2012.06.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.