Warren K. Miller;Daniel E. Dobry;Dwayne T. Friesen;David T. Vodak;David K. Lyon;William B. Caldwell
发明人:
Warren K. Miller,David K. Lyon,Dwayne T. Friesen,William B. Caldwell,David T. Vodak,Daniel E. Dobry
申请号:
US13702331
公开号:
US09040033B2
申请日:
2011.06.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility active agent and such polymers, the polymers provide increased aqueous concentrations and/or improved physical stability of the active agent.