A fluid delivery device (1000) comprises: a first subcutaneously insertable element with a distal portion (28) for subcutaneous placement within a human body, the subcutaneous insertable element comprising a cannula (66) with first and second electrodes (120,122) disposed on an inner or outer surface thereof a sensor (2000) that electrochemically interacts with one or more analytes and generates a signal that is representative of a concentration of the one or more analytes, the sensor being disposed on or within the distal portion (28) of the first subcutaneously insertable element and an external device (1001), (1002, 1003) in mechanical contact with a proximal portion (27) of the first subcutaneously insertable element, the external device comprising: a processor (1007) that receives and processes the signal from the sensor (2000) to determine the concentration of the one or more analytes within the human body and a delivery subsystem for delivering a therapeutic fluid via a second subcutaneously insertable element.【課題】【解決手段】例えばインスリンのような1以上の治療液が人体に供給できる。加えて、又は選択的に、体内の1以上の分析対象物の濃度が測定可能である。フィードバック処理が使用され、測定値に基づき、1以上の治療液の供給により、1以上の分析対象物のレベルが調整される。関連するシステム、装置、方法及び/又は製品も記述されている。【選択図】図13
