Dai Cheng,Dong Han,Guobao Zhang,Yongqin Wan,Yun Feng Xie,Jiqing Jiang,Wenqi Gao,Shifeng Pan
申请号：
US13060426
公开号：
US08507491B2
申请日:
2009.08.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides a method, compounds and compositions for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or GIi gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula (I).
