Wenqi Gao,Jiqing Jiang,Yongqin Wan,Dai Cheng,Dong Han,Xu Wu,Shifeng Pan
申请号：
US12299290
公开号：
US08178563B2
申请日:
2007.05.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides a method for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula I.
