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LIPIDATED IMIDAZOQUINOLINE DERIVATIVES
专利权人:
GlaxoSmithKline Biologicals SA
发明人:
JOHNSON, DAVID
申请号:
PL09822779
公开号:
PL2341933T3
申请日:
2009.10.23
申请国别(地区):
PL
年份:
2018
代理人:
摘要:
The compounds of the subject invention are adjuvant molecules that comprise a imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.
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