LIPIDATED IMIDAZOQUINOLINE DERIVATIVES

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专利权人:

GlaxoSmithKline Biologicals SA

发明人:

JOHNSON David,JOHNSON David

申请号：

SI200931796

公开号：

SI2341933T1

申请日:

2009.10.23

申请国别(地区):

SI

年份:

2018

代理人:

摘要：

The compounds of the subject invention are adjuvant molecules that comprise a imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.

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