Kevin R. Lynch,Timothy L. Macdonald,Thomas P. Mathews,Andrew Kennedy,Yugesh Kharel
申请号:
US15242330
公开号:
US09908849B2
申请日:
2016.08.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.