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ORAL E. COLI VECTOR-BASED VACCINE FOR PREVENTION OF COCCIDIOSIS IN POULTRY
专利权人:
US Biologic;The United States of America, as represented by the Secretary of Agriculture
发明人:
HYUN S. LILLEHOJ,WOOHYUN KIM,CHRIS PRZYBYSZEWSKI,D.STEVEN ZATECHKA, JR.
申请号:
US15828778
公开号:
US20180153945A1
申请日:
2017.12.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to recombinant vaccines capable of presenting all, or antigenic portions of, the Eimeria tenella 3-1e, or profilin. Also provided are methodologies of using the vaccines for oral administration to poultry and other targets in the control of coccidiosis. In particular embodiments, recombinant host cells, such as E. coli, expressing all or part of the 3-1e antigen, are provided that can be used as whole-cell vaccines. In some instances, the native 3-1e protein utilized in the vaccines presented herein is molecularly manipulated.
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