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Tetracycline-regulated gene expression in HSV-1 vectors
专利权人:
发明人:
Feng Yao
申请号:
US14823669
公开号:
US09745599B2
申请日:
2015.08.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to HSV-1 vectors which rely on the tetracycline repressor and operator as a means for regulating expression. The vectors utilize VP-16 responsive promoters of HSV to control expression of the tetracycline repressor. The vectors are of particular interest as vehicles for recombinantly expressing genes in vivo.
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