<；P>；PROBLEM TO BE SOLVED: To provide an ophthalmic composition such as an eye drop composition useful for the prevention, moderation and cure of dry eye symptom and an artificial tear liquid composition useful also as the artificial tear liquid. <；P>；SOLUTION: This ophthalmic composition contains a poly-&gamma；-glutamic acid as a component. The composition contains the poly-&gamma；-glutamic acid in which the poly-&gamma；-glutamic acid is an acid type, a salt type, a mixed type of the acid and salt types, a cross-linked type or a mixture of them, as its component, and further, may contain fructan and hyaluronic acid. Also, the poly-&gamma；-glutamic acid has &ge；30,000 molecular weight and is obtained from the culture of Natto bacillus. and it may contain a poly-&gamma；-glutamic acid hyaluronic acid obtained by bonding the poly-&gamma；-glutamic acid and hyaluronic acid. Also, the ophthalmic composition may be a contact lens-immersing liquid, ophthalmic gel or ophthalmic ointment. <；P>；COPYRIGHT: (C)2007,JPO&INPIT
