ЛЕРХЕН Ханс-Георг (DE),КАНЧО-ГРАНДЕ Йоланда (DE),ШТЕЛЬТЕ-ЛЮДВИГ Беатрикс (DE),ЗОММЕР Анетте (DE),МАЛЕРТ Кристоф (DE),РЕБСТОК Анне-Софи (FR),ГРЕВЕН Зимоне (DE),ГРИБЕНОВ Нильс (DE),ТЕББЕ Ян (DE),КЕНШ Ол
申请号：
RU2018102358
公开号：
RU2018102358A
申请日:
2016.06.20
申请国别(地区):
RU
年份:
2019
代理人:
摘要：
The invention relates to site specific homogeneous binder drug conjugates of kinesin spindle protein inhibitors, to active metabolites of these conjugates, to processes for preparing these conjugates, to the use of these conjugates for the treatment and/or prophylaxis of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.
