LERCHEN HANS GEORG,CANCHO GRANDE YOLANDA,STELTE LUDWIG BEATRIX,SOMMER ANETTE,MAHLERT CHRISTOPH,REBSTOCK ANNE SOPHIE,GREVEN SIMONE,GRIEBENOW NILS,TEBBE JAN,KENSCH OLIVER
申请号:
IN201717044798
公开号:
IN201717044798A
申请日:
2017.12.13
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The invention relates to site specific homogeneous binder drug conjugates of kinesin spindle protein inhibitors to active metabolites of these conjugates to processes for preparing these conjugates to the use of these conjugates for the treatment and/or prophylaxis of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases in particular hyperproliferative and/or angiogenic disorders such as for example cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.