DÉRIVÉS DE 1,3,8-TRISUBSTITUÉ-1,3,8-TRIAZA-SPIRO[4.5]DÉCAN-4-ONE UTILISÉS COMME LIGANDS DU RÉCEPTEUR ORL-I DANS LE TRAITEMENT DE L'ANXIÉTÉ ET DE LA DÉPRESSION
The present invention is directed to novel 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor.