BERGHAUSEN, Joerg,KAPA, Prasad, Koteswara,MCKENNA, Joseph,SLADE, Joel,WU, Raeann,DU, Zhengming,STOWASSER, Frank
申请号：
HK12111776.3
公开号：
HK1171016B
申请日:
2012.11.19
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present technology provides novel anhydrous and hydrated crystalline forms of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea, amorphous and anhydrous crystalline polymorphs of its monophosphoric acid salt, and the hydrochloride salt, including its dihydrate. The present technology further provides methods for preparing the various forms, compositions containing them, and methods of treatment employing them.
