Kyungpook National University Industry-Academic Cooperation Foundation
发明人:
Byung-Heon Lee,Bodhraj Acharya
申请号：
US15687219
公开号：
US10421780B2
申请日:
2017.08.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
An autophagic cell targeted peptide and its use are described. More particularly, a polypeptide comprising an amino acid sequence represented by the general formula (I) and specifically binding to an autophagic cell and a composition for detecting autophagic cells comprising the same as an active ingredient are described. Also described are a drug delivery composition containing the same peptide as an active ingredient and a composition for imaging comprising the same peptide as an active ingredient. The peptide specifically binds to the cell membrane of autophagic cells and can be applied to various kinds of tissues and cells. The detection and imaging effect of autophagy is remarkable in vitro and in vivo.
