Kyungpook National University Industry-Academic Cooperation Foundation
发明人:
LEE, Byung-Heon,ACHARYA, Bodhraj
申请号：
EP16755929
公开号：
EP3263584A4
申请日:
2016.02.26
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to an autophagic cell targeted peptide and its use. More particularly, the present invention relates to a polypeptide comprising an amino acid sequence represented by the general formula (I) and specifically binding to an autophagic cell and a composition for detecting autophagic cells comprising the same as an active ingredient, a drug delivery composition containing the same as an active ingredient, and a composition for imaging comprising the same as an active ingredient. The peptide of the present invention specifically binds to the cell membrane of autophagic cells and can be applied to various kinds of tissues and cells. Also the detection and imaging effect of autophagy is remarkable in vitro and in vivo.
