ANDERSON, ANNALIESA SYBIL,DONALD, ROBERT G.K.,FLINT, MICHAEL JAMES,JANSEN, KATHRIN UTE,KITCHIN, NICHOLAS RANDOLPH EVERARD,MORAN, JUSTIN KEITH,PEDNEAULT, LOUISE,PRIDE, MICHAEL W.,RUPPEN, MARK EDWARD,WE
申请号：
CA3076961
公开号：
CA3076961A1
申请日:
2018.09.14
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
In one aspect, the invention relates to an immunogenic composition that includes a Clostridium difficile toxoid A and/or a C. difficile toxoid B, and methods of use thereof. In another aspect, the invention relates to a method for eliciting an immune response in a human against a C. difficile infection. The method includes administering to the human an effective dose of a composition, which includes a C. difficile toxoid, wherein the composition is administered at least two times, wherein the second administration is about 30 days after the first administration, and wherein the immune response against C. difficile toxin A and/or toxin B is sustained.
