Kathrin Ute Jansen,Annaliesa Sybil Anderson,Robert G.K. Donald,Michael James Flint,Nicholas Randolph Everard Kitchin,Justin Keith Moran,Louise Pedneault,Michael W. Pride,Mark Edward Ruppen,Christopher
申请号：
US16647124
公开号：
US20200254081A1
申请日:
2018.09.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
In one aspect, the invention relates to an immunogenic composition that includes a Clostridium difficile toxoid A and/or a C. difficile toxoid B, and methods of use thereof. In another aspect, the invention relates to a method for eliciting an immune response in a human against a C. difficile infection. The method includes administering to the human an effective dose of a composition, which includes a C. difficile toxoid, wherein the composition is administered at least two times, wherein the second administration is about 30 days after the first administration, and wherein the immune response against C. difficile toxin A and/or toxin B is sustained.
