A drug-filled synthetic resin ampule (1) has an ampule body (2) capable of standing by itself and a drug (6) accommodated inside the ampule body (2). The ampule body (2) has a tip part (3) positioned at an upper part thereof when the ampule body stands by itself, a hollow part (21) having a drug accommodation portion (23), and a breakable part (5) provided between a lower portion of the tip part (3) and an upper portion of the hollow part (21). The tip part (3) has pressing portions (31), (32) for guiding a pressing force applied thereto in a predetermined direction when an operation of breaking the breakable part (5) is performed. The hollow part (21) has a bottom surface part (4) for allowing the ampule body to stand by itself. The bottom surface part (4) has extension portions (41), (42) extended in predetermined directions (X-direction, Y-direction) in which the pressing force applied to the pressing portions (31), (32) is guided when an operation of pressing the pressing portions (31), (32) is performed to break the breakable part.