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MÉTHODE D'ACTIVATION DES CELLULES T POUR LE TRAITEMENT DU CANCER
专利权人:
Inc.;Good T Cells
发明人:
申请号:
EP18844804.7
公开号:
EP3666888A2
申请日:
2018.08.10
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a cancer-specific tumor antigen neoepitope represented by any one of SEQ ID NOs: 1 to 184, an antigen-presenting cell loaded with the neoepitope, and a method for activating T cells for cancer treatment using the antigen-presenting cell. An antigen-presenting cell, that is, a dendritic cell, loaded with a cancer-specific tumor antigen epitope provided in the present invention enables rapid and effective induction of differentiation and proliferation of cancer antigen-specific T cells, preferably memory T cells, and the memory T cells thus activated can treat a cancerous or neoplastic condition or prevent recurrence, progression, or metastasis of cancer while avoiding the defense mechanism of cancer cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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