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שיטות לטיפול בסרטן באמצעות תאי t משופעלים
专利权人:
SYZ CELL THERAPY CO.
发明人:
申请号:
IL25379517
公开号:
IL253795D0
申请日:
2017.08.02
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
Provided is a method of treating a cancer in an individual using activated T cells or PBMCs induced by antigen presenting cells (such as dendritic cells) loaded with a plurality of tumor antigen peptides. The method may further comprise administration of the antigen presenting cells loaded with the plurality of tumor antigen peptides to the individual. The methods may be used singly or in combination with an immune checkpoint inhibitor. Also provided are precision therapy methods customized for the individual using neoantigen peptides or based on the mutation load in the tumor of the individual, methods of preparing the activated T cells, methods of monitoring the treatment, methods of cloning tumor-specific T cell receptors, an isolated population of cells comprising the activated T cells, and compositions and kits useful for cancer immunotherapy.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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