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AMINO ALCOHOL DERIVATIVES FOR THE TREATMENT OF DEMYELINATING PERIPHERAL NEUROPATHIES
专利权人:
发明人:
David LEPPERT,Erik WALLSTROEM,Barbara NEUSSLEIN-HILDESHEIM
申请号:
US15806845
公开号:
US20180064660A1
申请日:
2017.11.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides the use of compound of formula V or formula VI in the treatment of a demyelinating peripheral neuropathy:Wherein X, R1, R2, R3, R4, R5, n, R1a, R2a, R3a, R4a, R5a, R6a, R7a, X8, and na are defined herein or the N-oxide derivatives thereof or prodrugs thereof, or a pharmaceutically acceptable salt, solvate or hydrate thereof. The invention further provides combinations of a compound of Formula V or VI with one or more therapeutic agents and pharmaceutical composition thereof.
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