Anticorps dirigés contre l'ERBB3 et leurs utilisations

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专利权人:

Merrimack Pharmaceuticals; Inc.

发明人:

申请号：

EP13174963.2

公开号：

EP2647388A1

申请日:

2008.02.15

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The invention provides an isolated monoclonal antibody or antigen binding portion thereof that binds to human ErbB3 and comprises: (a) a heavy chain variable region comprising the amino acid sequence of SEQ ID NO: 1 and a light chain variable region comprising the amino acid sequence of SEQ ID NO: 2； or (b) a heavy chain variable region comprising an amino acid sequence which is at least 80% identical to the amino acid sequence of SEQ ID NO: 1 and a light chain variable region comprising an amino acid sequence which is at least 80% identical to the amino acid sequence of SEQ ID NO: 2.

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