FORMES CRISTALLINES DE SEL DE SODIUM DE 5-AMINO-2,3-DIHYDROPHTHALAZINE-1,4-DIONE, PREPARATIONS PHARMACEUTIQUES RENFERMANT DE TELLES FORMES,METH ODE DE PRODUCTION DESDITES FORMES ET UTILISATION DESDITESFORME POUR LA MODULATION DU SYSTEME IMMUNITAIRE
BREU, JOSEF,BRYSCH, WOLFGANG,KAISER, ASTRID,LUDESCHER, BEATE,MAASS, GERRIT,MARTIN, THOMAS,MILIUS, WOLFGANG,NIEDERMAIER, MICHAEL
申请号：
CA2791327
公开号：
CA2791327C
申请日:
2011.03.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention relates to the provision of twonovel crystalline forms I and II for5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt.Surprisingly, it was discovered that form I and form IIhave differing immunological effects. Thisadvantageous property is useful for immunospecificapplications. In addition, both forms have advantageousphysicochemical properties, which are useful in theproduction, further processing and/or use of apharmaceutical preparation of form I or form II or amixture of both.
