PROBLEM TO BE SOLVED: To provide an energy substraction processing apparatus which performs more accurate energy subtraction processing in accordance with grid use conditions at the time of imaging.SOLUTION: In the energy subtraction processing to perform a weighted addition or subtraction on corresponding pixels in a plurality of the radiation images by use of a given weight factor, a weight factor determining part 33 acquires grid information G1 representing the grid use conditions at the time of imaging a plurality of radiation images and determines the weight factor W3 from the acquired grid information G1, and a constituent image forming part 35 performs the weighted addition or subtraction by use of the weight factor W3.COPYRIGHT: (C)2010,JPO&INPIT【課題】撮影時のグリッドの使用状態に応じて、より適切なエネルギーサブトラクション処理を実現する。【解決手段】複数の放射線画像の相対応する画素毎に所与の重みづけ係数を用いた重み付き加減算を行うエネルギーサブトラクション処理の際に、重みづけ係数決定部33が、複数の放射線画像の撮影の際のグリッドの使用状態を表すグリッド情報G1を取得し、取得されたグリッド情報G1に基づいて重みづけ係数W3を決定し、成分画像生成部35が、この重みづけ係数W3を用いた重み付き加減算を行う。【選択図】図3