PROTEINES DE FUSION DE FRAGMENTS DE PROTEINES HUMAINES UTILISEES AFIN DE CREER DES COMPOSITIONS FC D'IMMUNOGLOBULINE MULTIMERISEE DE MANIERE ORDONNEE AVEC UNE LIAISON DE COMPLEMENT AMELIOREE

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专利权人:

GLIKNIK INC.

发明人:

BLOCK, DAVID S.,OLSEN, HENRIK

申请号：

CA2991254

公开号：

CA2991254A1

申请日:

2016.07.22

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The current invention involves a series of fully recombinant multimerized forms of immunoglobulin Fc which thereby present polyvalent immunoglobulin Fc to immune cell receptors. The fusion proteins exist as both homodimeric and highly ordered multimeric fractions, termed stradomers. The invention involves stradomers that increase multimerization and bind preferentially to complement and that are useful in the treatment and prevention of disease.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/