A device for securing a nasal cannula to a patient includes a pair of opposing legs having a predefined opening therebetween and a clip secured to an opposite end of the pair of opposing legs. The pair of opposing legs are configured to slide over a nasal septum and are biased together to provide compression as the pair of legs are moved apart when sliding over the nasal septum. The clip has an opening configured to secure the device to a tube. Alternatively, a device for securing a nasal cannula to a patient includes an adhesive strip configured to be releasably attached to columella of the nasal septum and a clip secured to the adhesive strip and the clip has an opening configured to secure the device to a tube.