Tarek A. Zeidan,David Manser,Kristopher Perkin,Philip Cresswell,Magali Hickey,Brian Steinberg
申请号:
US15435170
公开号:
US10159671B2
申请日:
2017.02.16
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein is a composition comprising: (a) a first population of particles of a first aripiprazole prodrug and (b) a second population of particles of a second aripiprazole prodrug, different to the first aripiprazole prodrug. At least one of the first and second prodrug populations has a volume based particle size (Dv50) of less than about 1000 nm. Also described herein are methods of treatment using the aforementioned composition, and methods of making the aforementioned composition.