Anna Zumsteg,Christos Kyratsous,Brinda Prasad,Alida Coppi
申请号：
US16689593
公开号：
US20200157193A1
申请日:
2019.11.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Speciated antibodies or antigen-binding fragments that bind staphylococcal antigens are provided, where the antibodies and antigen-binding fragments have attenuated Fc binding to Protein A or homologous protein. Compositions comprising the antibodies and methods of use are also provided. The antibodies and compositions are useful for treating staphylococcal infection, reducing serum or kidney bacterial titers, and treating symptoms associated with staphylococcal infection. The antibodies may also prevent the severity and/or duration of the primary disease.
