Antibodies having Fab regions that specifically bind to Staphylococcus aureus protein A are capable of mediating opsinization of Staphylococcus aureus bacteria despite their expression of antibody-neutralizing protein A. These antibodies and antigen-binding fragments thereof can be used in methods of treating and/or preventing Staphylococcus aureus infections.La presente solicitud hace referencia a composiciones que comprenden anticuerpos que se unen especificamente a la proteina A de staphylococcus aureus.