THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
GAISINA, IRINA,KOZIKOWSKI, ALAN
申请号：
CA3056448
公开号：
CA3056448A1
申请日:
2018.04.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Compounds that inhibit histone (HDACI) and/or activate Nrf2 and HIF, and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC and/or activation of Nrf2 and HIF provide a benefit, like a cancer, a neurodegenerative disorder, a peripheral neuropathy, a neurological disease, traumatic brain injury, stroke, hypertension, malaria, an autoimmune disease, autism, autism spectrum disorders, and inflammation, also are disclosed.
