THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
Irina Gaisina,Alan Kozikowski
申请号:
US16603266
公开号:
US20200039933A1
申请日:
2018.04.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compounds that inhibit histone (HDACI) and/or activate Nrf2 and HIF, and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC and/or activation of Nrf2 and HIF provide a benefit, like a cancer, a neurodegenerative disorder, a peripheral neuropathy, a neurological disease, traumatic brain injury, stroke, hypertension, malaria, an autoimmune disease, autism, autism spectrum disorders, and inflammation, also are disclosed.