CD138-TARGETED INTERFERON DEMONSTRATES POTENT APOPTOTIC AND ANTI-TUMOR ACTIVITIES

• 收藏
• 分享

专利权人:

发明人:

Sherie L. Morrison

申请号：

US15789828

公开号：

US20180162948A1

申请日:

2017.10.20

申请国别(地区):

US

年份:

2018

代理人:

摘要：

In various embodiments chimeric moieties (constructs) are provided that show significant efficacy against cancers. In certain embodiments the constructs comprise a targeting moiety that specifically binds CD138 attached to an interferon or to a mutant interferon. In certain embodiments, the constructs comprise anti-CD138 antibody attached to an interferon alpha (IFN-α) or to a mutant interferon alpha.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/