Disclosed by the invention is lower formula (I) compound: wherein R1, R2, R3, R4, R5, R6, R7, X and t are defined in the present specification. It is also disclosed that pharmaceutical composition, kit and manufacture comprising such compound, the method and intermediate of such compound are prepared with what, and use this compounds for treating and the related disease of PARP activity, the method for illness and the patient's condition.本發明公開的是下式(I)化合物：其中R1、R2、R3、R4、R5、R6、R7、X和ｔ在本說明書中所定義。還公開的是包含此類化合物的藥物組合物、試劑盒和製造品，用於製備此類化合物的方法和中間體，以及使用此類化合物治療與PARP活性有關的疾病、病症和病況的方法。
