Xiaoming Shen;Michael D. Bentley;Tony L. Sander;Antoni Kozlowski;Zhihao Fang
发明人:
Antoni Kozlowski,Xiaoming Shen,Michael D. Bentley,Zhihao Fang,Tony L. Sander
申请号:
US13267619
公开号:
US20120027714A1
申请日:
2011.10.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Segmented water soluble polymers, containing a higher molecular weight segment linked to a lower molecular weight segment, are described. In one embodiment, the polymer segments are poly(ethylene glycol) segments. The segmented polymers are functionalized and are useful for conjugation to various moieties such as pharmacologically active substances. Also described are conjugates of such polymers and methods of their preparation.