ANDREAS KOCH,CHRISTOPH SCHMITZ,MICHAEL HORSTMANN,MOHAMMAD SAMETI
申请号:
BRPI0909936
公开号:
BRPI0909936A2
申请日:
2009.06.16
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention relates to a composition for transdermal delivery, particularly iontophoretic transdermal delivery, of at least one cationic active agent or a salt thereof, said composition comprising said at least one cationic active agent or a salt thereof, at least one polyamine or/and polyamine salt, water or an aqueous solvent mixture, and optionally one or more additives. The invention further relates to the use of said composition as a component of a transdermal patch or of an iontophoretic transdermal patch, and to the use of said composition in a method for transdermally or iontophoretically administering cationic active agents, and to a method for determining the in vitro skin permeation properties of an active agent-containing iontophoretic composition.