HERBAL POWERS CORPORATION;JUAN L HANCKE OROZCO;RAFAEL BURGOS
发明人:
JUAN L HANCKE OROZCO,RAFAEL BURGOS
申请号:
BR112014015178
公开号:
BR112014015178A2
申请日:
2012.12.19
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The effectiveness of interferon for treating multiple sclerosis and other demyelinating diseases is synergistically potentiated by concomitant administration of a compound of Formula (I): wherein R1 is H, alkyl or OH, R2 is hydroxyalkyl or alkyl-O-L1, R3 is H or OH, X is C(═CH2), CH(OH), or spirooxirane-2, Z is CH2CH(OH) or C(=0), and R4 is an optionally substituted L2-alkyl or L2-alkenyl, wherein L2 is an optionally substituted 3-furanyl or 3-fur-3-enyl moiety.