Method for treating demyelinating disease such as Multiple Sclerosis and a andrografolidos compounds which comprises administering interferon； and Use thereof for treating demyelinating disease such as multiple sclerosis.
The effectiveness of interferon for treating multiple sclerosis and other demyelinating diseases is synergistically potentiated by concomitant administration of a compound of Formula (I): wherein R1 is H, alkyl or OH, R2 is hydroxyalkyl or alkyl-O-L1, R3 is H or OH, X is C(&boxH；CH2), CH(OH), or spirooxirane-2, Z is CH2CH(OH) or C(=0), and R4 is an optionally substituted L2-alkyl or L2-alkenyl, wherein L2 is an optionally substituted 3-furanyl or 3-fur-3-enyl moiety.USO DE UN COMPUESTO DERIVADO DE ANDROGRAFOLIDO E INTERFERÓN PARA TRATAR UNA ENFERMEDAD DESMIELINIZANTE.
