A non-invasive diagnosis method for degenerative arthritis includes the following steps: first, extracting the vibration wave signal generated by bone friction when the human joint is in a range of motion angle; then converting the vibration wave signal into frequency signal by conversion model; then calculating the frequency-domain strength index corresponding to the frequency-domain signal by frequency-domain strength model; finally, calculating the frequency by analysis model Domain strength index was used to obtain the probability value of judging the incidence of degenerative arthritis.一種非侵入式退化性關節炎診斷方法,其步驟包括:首先,擷取人體關節在一活動角度範圍時由骨骼摩擦所產生的震動波訊號;接著藉由轉換模型將震動波訊號轉換為頻域訊號;接著藉由頻域強度模型計算頻域訊號所對應的頻域強度指數;最後藉由分析模型計算頻域強度指數以取得判斷退化性關節炎發生機率的機率值。