ROERINK, FRANK,法兰克 罗林克,法蘭克 羅林克,VAN WOENSEL, PETRUS ALPHONSUS MARIA,派翠斯 凡温塞尔,派翠斯 凡溫塞爾
申请号：
TW094131364
公开号：
TWI361695B
申请日:
2005.09.12
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The vaccine of the anti-2nd type Pig Ring Like of the bright Off whats Right of this Hair viral (PCV-2) and the method for making The vaccines for System to protect the anti-PCV-2 infection of the small Pig Right of Nursing. Now Yi Hair Now:Comprising the 2nd type Pig Ring Like of at least 20 micrograms/Elixirs amounts viral (PCV-2) though the vaccine of the white Quality of ORF-2 eggs in small Pig there is the MDA Time of the anti-PCV-2 of Right of phase When high-titers can still draw the guarantor Nursing immunizations (From and the anti-PMWS of Right) of the anti-PCV-2 of Right. This Hair of root According bright vaccine can contain the ORF-2 Dan Bai Quality of Chong Group, wherein The Chong Group Dan Bai Quality preferably make , The Rod Like Bing Du Biao Now Load Body by the Fang Shi System of From Kun Insect Fine born of the same parents Zhong Rod Like Bing Du Biao Now Load Body Biao Now and contain the The PCV-2 ORF-2 gene orders controlled Shou Kai Move of He Fitness.本發明關於對抗第二型豬環狀病毒(PCV-2)之疫苗及供製造該疫苗以保護小豬對抗PCV-2感染之方法。現已發現:包含至少20微克/劑量之第二型豬環狀病毒(PCV-2)的ORF-2蛋白質的疫苗即使在小豬具有相當高滴定度之對抗PCV-2的MDA時仍可引出對抗PCV-2之保護性免疫反應(從而對抗PMWS)。根據本發明之疫苗可含有重組之ORF-2蛋白質,其中該重組蛋白質宜藉由從昆蟲細胞中之桿狀病毒表現載體表現的方式製造,該桿狀病毒表現載體含有受合適之啟動子控制的該PCV-2 ORF-2基因序列。
