Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
发明人:
ALISI, Maria Alessandra,CAZZOLLA, Nicola,DRAGONE, Patrizia,FURLOTTI, Guido,MAUGERI, Caterina,OMBRATO, Rosella,MANCINI, Francesca
申请号：
MEP201629
公开号：
ME02353B
申请日:
2013.02.07
申请国别(地区):
ME
年份:
2016
代理人:
摘要：
The present invention relates to the 1H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3&bgr；) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders； (ii) neurodegenerative diseases； (iii) mood disorders； (iv) schizophrenic disorders； (v) cancerous disorders； (vi) inflammation, (vii) substance abuse disorders； (viii) epilepsies； and (ix) neuropathic pain.
