Irinotecan sensitivity determination method and use thereof

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专利权人:

株式会社ヤクルト本社

发明人:

西山 正彦,檜山 桂子,谷本 圭司

申请号：

JP2011503734

公开号：

JP5774473B2

申请日:

2010.03.12

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

To provide a method for determining the sensitivity of a patient to irinotecan, SN-38, and/or a salt thereof, which method can determine the therapeutic response of the patient and to provide a novel cancer therapeutic means employing the method. The method for determining the sensitivity of a subject to irinotecan, SN-38, and/or a salt thereof includes measuring the expression levels of AMD1 gene, CTSC gene, EIF1AX gene, C12orf30 gene, DDX54 gene, PTPN2 gene, and TBX3 gene in a specimen, and calculating the best tumor response rate (%), overall survival (days), or progression-free survival (days) from formulas (1) to (3).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/