"method for determining sensitivity to irinotecan and use thereof"

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专利权人:

发明人:

MASAHIKO NISHIYAMA,KEIKO HIYAMA,KEIJI TANIMOTO

申请号：

IN6624/DELNP/2011

公开号：

IN2011DN06624A

申请日:

2011.08.30

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

To provide a method for determining the sensitivity of a patient to irinotecan, SN-38, and/or a salt thereof, which method can determine the therapeutic response of the patient and to provide a novel cancer therapeutic means employing the method. The method for determining the sensitivity of a subject to irinotecan, SN-38, and/or a salt thereof includes measuring the expression levels of AMD1 gene, CTSC gene, EIF1AX gene, C12orf30 gene, DDX54 gene, PTPN2 gene, and TBX3 gene in a specimen, and calculating the best tumor response rate (%), overall survival (days), or progression-free survival (days) from formulas (1) to (3) .

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/