LERICHE CAROLINE,AUCLAIR ERIC,LE ROUX JACQUES,MIDDLEMISS DAVID N
申请号:
ZA201104777
公开号:
ZA201104777B
申请日:
2011.06.28
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The invention is directed to certain novel compounds, methods for producing them and methods for treating or ameliorating a kinase-mediated disorder. More particularly, this invention is directed to substituted quinazoline compounds useful as selective kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase-mediated disorder, In particular, the methods relate to treating or ameliorating a kinase-mediated disorder including cardiovascular diseases, diabetes, diabetes-associated disorders, inflammatory diseases, immunological disorders, cancer and diseases of the eye such as retinopathies or macular degeneration or other vitreoretinal diseases, and the like.