CAROLINE LERICHE,DAVID N. MIDDLEMISS,ERIC AUCLAIR,JACQUES LE ROUX
申请号：
BRPI0924067
公开号：
BRPI0924067A2
申请日:
2009.12.18
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The invention is directed to certain novel compounds, methods for producing them and methods for treating or ameliorating a kinase-mediated disorder. More particularly, this invention is directed to substituted quinazoline compounds useful as selective kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase-mediated disorder, In particular, the methods relate to treating or ameliorating a kinase-mediated disorder including cardiovascular diseases, diabetes, diabetes-associated disorders, inflammatory diseases, immunological disorders, cancer and diseases of the eye such as retinopathies or macular degeneration or other vitreoretinal diseases, and the like.
