Patrick S. Stayton;Robert W. Overell;Anthony J. Convertine;Paul H. Johnson;Allan S. Hoffman;Craig L. Duvall
发明人:
Patrick S. Stayton,Allan S. Hoffman,Anthony J. Convertine,Craig L. Duvall,Robert W. Overell,Paul H. Johnson
申请号：
US13127968
公开号：
US08822213B2
申请日:
2009.05.13
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.
