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PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO DAMAGE
专利权人:
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;CLIO, INC.;TOHOKU UNIVERSITY
发明人:
Mari Dezawa,YOSHINORI FUJIYOSHI,MASANORI YOSHIDA
申请号:
US15642534
公开号:
US20170304326A1
申请日:
2017.07.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The purpose of the present invention is to identify a migratory factor that guides pluripotent stem cells (Muse cells) useful in new medical applications to damage, and to provide a pharmaceutical composition that includes the migratory factor for promoting tissue regeneration in regenerative medicine that makes use of Muse cells. In the present invention, a receptor that is specifically expressed in Muse cells rather than non-Muse cells was identified, and it was confirmed that a ligand for this receptor can function as a migratory factor. In the present invention, sphingosine-1-phosphate (S1P) was identified as a migratory factor, and thus, the present invention pertains to a pharmaceutical composition for guiding pluripotent stem cells to damage, the composition including S1P as an active ingredient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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