ANN M. BULLION,BRIAN EVANS,HUIJIE LI,JAKOB BUSCH-PETERSEN,MICHAEL D. WALL,MICHAEL R. PALOVICH,NEYSA NEVINS,NIALL ANDERSON,STEVEN L. SOLLIS
申请号:
BR112012003044
公开号:
BR112012003044A2
申请日:
2010.08.11
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.